5HT2A_HUMAN
General information
| Gene Name | HTR2A,HTR2 |
| Family | Serotonin type 2 |
| GPCRDB | 5HT2A_HUMAN |
| UniProt | P28223 |
| IUPHAR | 2320 |
| Entrez Gene | 3356 |
| KEGG | hsa:3356 |
| Sequence | 5HT2A_HUMAN.fasta |
TOP
Similarity Search
TOP
Binding information
Agonist
|
|
Name(s) |
dironyl |
| PubChem Compound | 37816 | |
| Formula | C20 H28 N4 O | |
| Mol. Wt. | 340.226 | |
| Cas No. | 37686-84-3 37686-85-4 85649-11-2 | |
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L000794.mol L000794.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:12388666 | |
|
|
Name(s) |
ORG 5222 |
| PubChem Compound | 163091 | |
| Formula | C17 H16 N O Cl | |
| Mol. Wt. | 285.092 | |
| Cas No. | 65576-45-6 | |
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L000898.mol L000898.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:8935801 | |
|
|
Name(s) |
Methylergonovine |
| PubChem Compound | 4140 | |
| Formula | C20 H25 N3 O2 | |
| Mol. Wt. | 339.194 | |
| Cas No. | ||
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L000928.mol L000928.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:15322733 | |
|
|
Name(s) |
tryptamine |
| PubChem Compound | 1150 | |
| Formula | C10 H12 N2 | |
| Mol. Wt. | 160.100 | |
| Cas No. | 343-94-2 34685-69-3 61-54-1 | |
| KEGG | C00398 | |
| ChEBI | 16765 | |
| DrugBank | ||
| Struct. file | L000946.mol L000946.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:2233697 PMID:8114677 PMID:15322733 PMID:9225287 PMID:7984267 PMID:10498829 | |
|
|
Name(s) |
Quipazine |
| PubChem Compound | 5011 | |
| Formula | C13 H15 N3 | |
| Mol. Wt. | 213.127 | |
| Cas No. | 4774-24-7 5786-68-5 | |
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L000958.mol L000958.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:15322733 | |
|
|
Name(s) |
1-(3-trifluoromethylphenyl)-2-propanol |
| PubChem Compound | 150791 | |
| Formula | C10 H11 O F3 | |
| Mol. Wt. | 204.076 | |
| Cas No. | 621-45-4 | |
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L001044.mol L001044.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:15322733 | |
|
|
Name(s) |
MK 212 |
| PubChem Compound | 107992 | |
| Formula | C8 H11 N4 Cl | |
| Mol. Wt. | 198.067 | |
| Cas No. | 61655-58-1 64022-27-1 | |
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L001055.mol L001055.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:15322733 | |
|
|
Name(s) |
roxindole |
| PubChem Compound | 219050 | |
| Formula | C23 H26 N2 O | |
| Mol. Wt. | 346.204 | |
| Cas No. | 112192-04-8 | |
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L001062.mol L001062.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:12388666 | |
|
|
Name(s) |
Alpha Methyl 5 Hydroxytryptamine |
| PubChem Compound | 2107 | |
| Formula | C11 H14 N2 O | |
| Mol. Wt. | 190.111 | |
| Cas No. | ||
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L001159.mol L001159.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:15322733 | |
|
|
Name(s) |
2,4-dihydroxybenzylamine beta-resorcylic acid |
| PubChem Compound | 1491 | |
| Formula | C7 H6 O4 | |
| Mol. Wt. | 154.027 | |
| Cas No. | 17289-70-2 41453-50-3 89-86-1 | |
| KEGG | ||
| ChEBI | ||
| DrugBank | ||
| Struct. file | L001160.mol L001160.kegg | |
| Activity | Full Agonist | |
| Reference | PMID:11562430 PMID:8534270 | |