5HT4R_HUMAN

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Agonist

Name(s) Serotonin
thrombocytin
PubChem Compound 5202
Formula C10 H12 N2 O
Mol. Wt. 176.095
Cas No. 50-67-9 
KEGG C00780
ChEBI 28790 
DrugBank  
Struct. file L000078.mol  L000078.kegg
Activity Full Agonist
Reference PMID:9603189 PMID:10683202 PMID:11218067 PMID:10646498 PMID:8867105 PMID:9349523
Name(s) 5-Methoxytryptamine
PubChem Compound 1833
Formula C11 H14 N2 O
Mol. Wt. 190.111
Cas No. 608-07-1 
KEGG C05659
ChEBI  
DrugBank  
Struct. file L000647.mol  L000647.kegg
Activity Full Agonist
Reference PMID:9603189 PMID:9349523 PMID:10646498 PMID:10683202 PMID:11030734 PMID:11218067 PMID:8867105
Name(s) (endo-N-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2,3-dihydro-3-isopropyl-2-oxo-1H-benzimidaz
 ol-1-carboxamide
PubChem Compound 131724
Formula C19 H27 N4 O2 Cl
Mol. Wt. 378.182
Cas No. 134296-40-5 
KEGG  
ChEBI  
DrugBank  
Struct. file L000648.mol  L000648.kegg
Activity Full Agonist
Reference
Name(s) 2-piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate
PubChem Compound 5311299
Formula C15 H21 N2 O3 Cl
Mol. Wt. 312.124
Cas No.  
KEGG  
ChEBI  
DrugBank  
Struct. file L000650.mol  L000650.kegg
Activity Partial Agonist
Reference PMID:9603189
Name(s) RS 67506
PubChem Compound 133075
Formula C18 H29 N3 O4 S Cl2
Mol. Wt. 453.125
Cas No. 168986-61-6 
KEGG  
ChEBI  
DrugBank  
Struct. file L000652.mol  L000652.kegg
Activity Agonist
Reference
Name(s) SC 53116
PubChem Compound 132337
Formula C16 H22 N3 O2 Cl
Mol. Wt. 323.140
Cas No. 141196-99-8 
KEGG  
ChEBI  
DrugBank  
Struct. file L000654.mol  L000654.kegg
Activity Agonist
Reference
Name(s) prucalopride
PubChem Compound 3052762
Formula C18 H26 N3 O3 Cl
Mol. Wt. 367.166
Cas No. 179474-81-8 
KEGG  
ChEBI  
DrugBank  
Struct. file L000891.mol  L000891.kegg
Activity Partial Agonist
Reference PMID:10646498 PMID:11438309
Name(s) mosapride
PubChem Compound 119584
Formula C21 H25 N3 O3 Cl F
Mol. Wt. 421.156
Cas No. 112885-41-3 
KEGG D01994
ChEBI  
DrugBank  
Struct. file L000932.mol  L000932.kegg
Activity Full Agonist
Reference PMID:10646498
Name(s) Cisapride
PubChem Compound 2769
Formula C23 H29 N3 O4 Cl F
Mol. Wt. 465.183
Cas No. 81098-60-4 86718-68-5 
KEGG C06910
ChEBI  
DrugBank APRD00454
Struct. file L000938.mol  L000938.kegg
Activity Partial Agonist
Reference PMID:9349523 PMID:10646498 PMID:7796807 PMID:10683202 PMID:11030734 PMID:11218067 PMID:8867105
Name(s) renzapride
PubChem Compound 3086547
Formula C16 H22 N3 O2 Cl
Mol. Wt. 323.140
Cas No. 112727-80-7 
KEGG  
ChEBI  
DrugBank  
Struct. file L001036.mol  L001036.kegg
Activity Full Agonist
Reference PMID:9603189 PMID:9351641 PMID:7796807 PMID:10683202 PMID:11030734 PMID:11218067