5HT6R_HUMAN

General information

5HT6R_HUMAN
Gene Name	HTR6
Family	Serotonin type 6
GPCRDB	5HT6R_HUMAN
UniProt	P50406
IUPHAR	2335
Entrez Gene	3362
KEGG	hsa:3362
Sequence	5HT6R_HUMAN.fasta

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Binding information

Agonist

L000077
	Name(s)	5-carboxamidotryptamine
	PubChem Compound	1809
	Formula	C11 H13 N3 O
	Mol. Wt.	203.106
	Cas No.	74885-09-9
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000077.mol L000077.kegg
	Activity	Full Agonist
	Reference	PMID:8522988 PMID:8226867

L000078
	Name(s)	Serotonin thrombocytin
	PubChem Compound	5202
	Formula	C10 H12 N2 O
	Mol. Wt.	176.095
	Cas No.	50-67-9
	KEGG	C00780
	ChEBI	28790
	DrugBank
	Struct. file	L000078.mol L000078.kegg
	Activity	Full Agonist
	Reference	PMID:8522988 PMID:9284367 PMID:9730917 PMID:8226867 PMID:14645659

L000142
	Name(s)	BRL15572
	PubChem Compound	3654103
	Formula	C25 H27 N2 O Cl
	Mol. Wt.	406.181
	Cas No.
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000142.mol L000142.kegg
	Activity	Partial Agonist
	Reference	PMID:9303567

L000275
	Name(s)	GR 127935
	PubChem Compound	107780
	Formula	C29 H31 N5 O3
	Mol. Wt.	497.242
	Cas No.	148672-13-3
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000275.mol L000275.kegg
	Activity	Partial Agonist
	Reference	PMID:9303567

L000349
	Name(s)	Lisuride
	PubChem Compound	28864
	Formula	C20 H26 N4 O
	Mol. Wt.	338.210
	Cas No.	18016-80-3 19875-60-6
	KEGG	D01462
	ChEBI
	DrugBank	APRD00636
	Struct. file	L000349.mol L000349.kegg
	Activity	Full Agonist
	Reference	PMID:9284367 PMID:9730917

L000352
	Name(s)	Lysergic Acid Diethylamide Vitamin A
	PubChem Compound	5761
	Formula	C20 H25 N3 O
	Mol. Wt.	323.199
	Cas No.	50-37-3
	KEGG	C07542
	ChEBI
	DrugBank
	Struct. file	L000352.mol L000352.kegg
	Activity	Full Agonist
	Reference	PMID:9730917 PMID:9284367 PMID:14645659

L000647
	Name(s)	5-Methoxytryptamine
	PubChem Compound	1833
	Formula	C11 H14 N2 O
	Mol. Wt.	190.111
	Cas No.	608-07-1
	KEGG	C05659
	ChEBI
	DrugBank
	Struct. file	L000647.mol L000647.kegg
	Activity	Full Agonist
	Reference	PMID:8522988 PMID:8226867 PMID:14645659

L000694
	Name(s)	xanomeline
	PubChem Compound	60809
	Formula	C14 H23 N3 O S
	Mol. Wt.	281.156
	Cas No.	131986-45-3
	KEGG	C11767
	ChEBI
	DrugBank
	Struct. file	L000694.mol L000694.kegg
	Activity	Full Agonist
	Reference	PMID:9884068

L000746
	Name(s)	F 11356
	PubChem Compound	197706
	Formula	C23 H25 N5 O2
	Mol. Wt.	403.200
	Cas No.	170912-52-4
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000746.mol L000746.kegg
	Activity	Partial Agonist
	Reference	PMID:10381763

L000768
	Name(s)	Ergotamine
	PubChem Compound	3251
	Formula	C33 H35 N5 O5
	Mol. Wt.	581.263
	Cas No.	113-15-5
	KEGG
	ChEBI
	DrugBank	APRD00677
	Struct. file	L000768.mol L000768.kegg
	Activity	Full Agonist
	Reference	PMID:9284367 PMID:9730917