5HT1B_HUMAN

General information

5HT1B_HUMAN
Gene Name	HTR1B,HTR1DB
Family	Serotonin type 1
GPCRDB	5HT1B_HUMAN
UniProt	P28222
IUPHAR	2312
Entrez Gene	3351
KEGG	hsa:3351
Sequence	5HT1B_HUMAN.fasta

TOP

Similarity Search

TOP

Binding information

Agonist

L000061
	Name(s)	2-methyl-5-HT
	PubChem Compound	1574
	Formula	C11 H14 N2 O
	Mol. Wt.	190.111
	Cas No.	78263-90-8
	KEGG	C13665
	ChEBI
	DrugBank
	Struct. file	L000061.mol L000061.kegg
	Activity	Full Agonist
	Reference	PMID:1565658

L000077
	Name(s)	5-carboxamidotryptamine
	PubChem Compound	1809
	Formula	C11 H13 N3 O
	Mol. Wt.	203.106
	Cas No.	74885-09-9
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000077.mol L000077.kegg
	Activity	Full Agonist
	Reference	PMID:1565658 PMID:8863519 PMID:1315531 PMID:9303569 PMID:7984267

L000078
	Name(s)	Serotonin thrombocytin
	PubChem Compound	5202
	Formula	C10 H12 N2 O
	Mol. Wt.	176.095
	Cas No.	50-67-9
	KEGG	C00780
	ChEBI	28790
	DrugBank
	Struct. file	L000078.mol L000078.kegg
	Activity	Partial Agonist
	Reference	PMID:1565658 PMID:11040052 PMID:8957260 PMID:8863519 PMID:1315531 PMID:9303567 PMID:9303569 PMID:9776361 PMID:7984267

L000086
	Name(s)	8-Hydroxy-2-(di-n-propylamino)tetralin
	PubChem Compound	1220
	Formula	C16 H25 N O
	Mol. Wt.	247.194
	Cas No.	78950-78-4
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000086.mol L000086.kegg
	Activity	Full Agonist
	Reference	PMID:9303569 PMID:1315531 PMID:7984267

L000142
	Name(s)	BRL15572
	PubChem Compound	3654103
	Formula	C25 H27 N2 O Cl
	Mol. Wt.	406.181
	Cas No.
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000142.mol L000142.kegg
	Activity	Partial Agonist
	Reference	PMID:9303567

L000195
	Name(s)	Clozapine
	PubChem Compound	2818
	Formula	C18 H19 N4 Cl
	Mol. Wt.	326.130
	Cas No.	5786-21-0
	KEGG	C06924
	ChEBI
	DrugBank	APRD00470
	Struct. file	L000195.mol L000195.kegg
	Activity	Full Agonist
	Reference	PMID:8935801 PMID:7520908

L000200
	Name(s)	3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one
	PubChem Compound	124007
	Formula	C12 H13 N3 O
	Mol. Wt.	215.106
	Cas No.	127792-75-0
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000200.mol L000200.kegg
	Activity	Agonist
	Reference

L000279
no data	Name(s)	3-(3-(dimethylamino)propyl)-4-hydroxy-N-(4-(4-pyridinyl)phenyl)benzamide
	PubChem Compound	128018
	Formula	C23 H25 N3 O2
	Mol. Wt.	375.194
	Cas No.
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000279.mol L000279.kegg
	Activity	Full Agonist
	Reference

L000336
	Name(s)	L 694247
	PubChem Compound	132059
	Formula	C20 H21 N5 O3 S
	Mol. Wt.	411.136
	Cas No.	137403-12-4
	KEGG
	ChEBI
	DrugBank
	Struct. file	L000336.mol L000336.kegg
	Activity	Full Agonist
	Reference	PMID:10513577

L000349
	Name(s)	Lisuride
	PubChem Compound	28864
	Formula	C20 H26 N4 O
	Mol. Wt.	338.210
	Cas No.	18016-80-3 19875-60-6
	KEGG	D01462
	ChEBI
	DrugBank	APRD00636
	Struct. file	L000349.mol L000349.kegg
	Activity	Full Agonist
	Reference	PMID:12388666